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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRAPL
All Species:
43.33
Human Site:
Y52
Identified Species:
79.44
UniProt:
Q8TC17
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC17
NP_001123250
118
13442
Y52
E
G
F
I
P
K
N
Y
I
R
V
K
P
H
P
Chimpanzee
Pan troglodytes
XP_529824
164
17412
Y52
E
G
F
I
P
K
N
Y
I
R
V
K
P
H
P
Rhesus Macaque
Macaca mulatta
XP_001097817
217
25285
Y52
E
G
F
I
P
K
N
Y
I
H
V
K
P
H
P
Dog
Lupus familis
XP_546653
217
25309
Y52
E
G
F
I
P
K
N
Y
I
R
I
K
P
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX99
217
25259
Y52
E
G
F
V
P
K
N
Y
I
R
V
K
P
H
P
Rat
Rattus norvegicus
P62994
217
25188
Y52
D
G
F
I
P
K
N
Y
I
E
M
K
P
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505772
217
25155
I52
E
S
F
F
Y
K
N
I
Q
K
L
S
P
S
P
Chicken
Gallus gallus
Q07883
217
25058
Y52
G
G
F
I
P
K
N
Y
I
E
M
K
P
H
P
Frog
Xenopus laevis
Q6GPJ9
229
26344
Y52
D
G
F
I
P
K
N
Y
I
E
M
K
P
H
P
Zebra Danio
Brachydanio rerio
NP_998200
217
25269
Y52
D
G
F
I
P
K
N
Y
I
E
M
K
A
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08012
211
24417
Y52
E
G
L
I
P
S
N
Y
I
E
M
K
N
H
D
Honey Bee
Apis mellifera
XP_623354
211
24679
Y52
E
G
L
I
P
S
N
Y
I
E
M
K
N
H
D
Nematode Worm
Caenorhab. elegans
P29355
228
26192
Y52
E
G
F
I
P
S
N
Y
I
R
M
T
E
C
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
51.6
50.2
N.A.
49.3
35.4
N.A.
37.7
35.4
31.4
35.4
N.A.
29.8
30.8
28
N.A.
Protein Similarity:
100
51.2
52.5
52
N.A.
51.1
44.2
N.A.
45.1
43.7
41.9
43.7
N.A.
40.2
40.2
39.9
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
80
N.A.
40
80
80
73.3
N.A.
60
60
60
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
53.3
86.6
93.3
86.6
N.A.
66.6
66.6
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% D
% Glu:
70
0
0
0
0
0
0
0
0
47
0
0
8
0
0
% E
% Phe:
0
0
85
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
85
0
% H
% Ile:
0
0
0
85
0
0
0
8
93
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
77
0
0
0
8
0
85
0
0
0
% K
% Leu:
0
0
16
0
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
100
0
0
0
0
0
16
0
8
% N
% Pro:
0
0
0
0
93
0
0
0
0
0
0
0
70
0
77
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
39
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
24
0
0
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
31
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _